In the face of the rapid developments in sleep medicine, this book seeks to present the current knowledge in the pathophysiology, clinical presentation, diagnosis, and treatment of sleep apnea. New physiological approaches to modeling sleep and recent pathophysiologic findings in upper airway mechanics as well as the importance of inflammatory and oxidative processes and the underlying genetic aspects are discussed to open up new avenues of investigation for better understanding and improved therapeutic options.
From the bestselling author of Hyperspace, this spellbinding book brings together the cutting-edge research of today's foremost scientists to explore the science of tomorrow. Michio Kaku describes the development of computers and artificial intelligence, reveals how the decoding of the genetic structure of DNA will allow us to alter and reshape our genetic inheritance, and observes how quantum physicists are perfecting new ways of harnessing the matter and energy of the Universe. Visions is an exhilarating adventure into the future of our planet and ourselves.
Long before Dolly the Sheep or bioengineered corn, there was the Red Canary-the first organism to be manipulated by genetic technology, back in the 1920s. The effort to produce a red canary invoked all of the deep issues that troubled genetic engineering decades later: the nature of genes and how they work, the specter of eugenics, and the relative roles of nature and nurture in determining what an organism is.
Substantially revised to reflect the changes in this rapidly developing field, this edition (the first edition came out in 1999) features 64 new essays, heavy revision of 131, and omission of 26, and new or updated bibliographies for all entries. Two new appendices have been added , on web sites and Nobel prizes. Among the topics included are altruism, ancient DNA, antibodies, bioethics, biological determinism, cancer, cell culture of plants and animals, diabetes, epistasis, eugenics, genetically modified foods, and pseudogenes. Several entries are devoted to case studies of model organisms, and there are multiple entries on aspects of DNA, gene regulation, gene therapy, genetic code, genetic engineering, and chromosomes. The contributors are academics, researchers, and independent scholars in the US.
Biology is often viewed today as a bipartisan field, with molecular level genetics guiding us into the future and natural history (including ecology, evolution, and conservation biology,) chaining us to a descriptive scientific past. In Darwinian Detectives, Norman Johnson bridges this divide, revealing how the tried and true tools of natural history make sense of the newest genomic discoveries. Molecular scientists exploring newly sequenced genomes have stumbled upon quite a few surprises, including that only one to ten percent of the genetic material of animals actually codes for genes. What does the remaining 90-99% of the genome do? Why do some organisms have a much lower genome size than their close relatives? What were the genetic changes that were associated with us becoming human? As molecular biologists uncover these and other new mysteries, evolutionary geneticists are searching for answers to such questions. Norman Johnson captures the excitement of the hunt for our own genetic history. Through lively anecdotes, he explores how researchers detect natural selection acting on genes and what this genetic information tells us about human origins.
