The book features current knowledge concerning mechanisms of metastasis, the role of the bone microenvironment in cancer progression, function of inflammatory cytokines in metastasis and osteolysis, the role of osteoblasts, thus offering cellular and molecular findings that affect the search for drugs and lead to translational studies.
Dark Visions is the British equivalent of the American 'Night Visions 5' and contains the same works by Stephen King 'The Reploids" - 'Sneakers' and 'Dedication' - Dan Simmons "Metastasis', 'Vanni Fucci.." and 'Iverson's Pits' - and George R.R. Martin's 'The Skin Trade'.
This volume is the first book to cover the general topic of targeted cancer therapy. It presents a range of targets such as tumor angiogenesis, cell cycle control and cell signalling, COX-2, apoptosis/cell survival, invasion and metastasis and approaches like kinase inhibitors, antisense, and antibody-based therapeutics.
