Extensively revised and updated, Antisense Drug Technology: Principles, Strategies, and Applications, Second Edition reflects the logarithmic progress made in the past four years of oligonucleotide-based therapies, and, in particular, antisense therapeutics and research. Interpreting lessons learned from the clinical trials of first generation drugs, the book evaluates the technology as a whole and offers new directions and avenues of research and development. Divided into five parts, the book begins with a thorough introduction to the mechanism of antisense drug action including the RNase H mechanism, small RNA silencing pathways, and the potential therapeutics of splice switching oligonucleotides. Leading researchers demonstrate the basics of oligonucleotide therapeutics in part two by delineating medicinal chemistry,
This third edition includes updates in manufacturing logistics, integrated logistics, process design and home delivery and brand new sections on warehouse receipt and dispatch. Also contains an thorough explanation of new technologies such as radio frequency identification (RFID), voice technology, satellite crane systems and dynamic pick systems.
Newton's Telecom Dictionary helps technology and business professionals stay on top of the ever-changing network, telecom, and IT industry. The tech industry hype has cooled dramatically, but nonetheless new telecom and networking technology and services continue to be adopted at a rapid pace, and new terms and acronyms sprout just as quickly. Industry guru Harry Newton explains technical concepts in non-technical language that anyone in business can understand, making it an essential reference tool for anyone involved with telecom and IT systems and services.
Added by: Maria | Karma: 3098.81 | Other | 6 July 2008
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Despite John Lennon's immense popularity, little attention has been paid to the overall efforts of his work apart from the Beatles. Yet his solo artistry not only illuminates what he gave to the Beatles (and what the Beatles experience gave to him), but also constitutes a significant contribution to popular music in general. Lennon was able to fuse experiments in technology, instrumentation, lyrics, and musical form into recordings that were both artistically and commercially successful.
Added by: Maria | Karma: 3098.81 | Periodicals | 2 July 2008
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Wired is a full-color monthly American magazine and on-line periodical published in San Francisco, California since March 1993.
Owned by Condй Nast Publications, it reports on how technology affects culture, the economy, and politics.