Investigating the Human Genome: Insights into Human Variation and Disease Susceptibility

An Up-to-Date Assessment of Recent Advances in Human Genetics, Human Variation,and Gene-Related Disease In Investigating the Human Genome, leading medical genetics scholar Moyra Smith reviews current and recent work in genetics and genomics to assess progress in understanding human variation and the pathogenesis of common and rare diseases in which genetics plays a role. Smith provides an exceptional overview of the most important biomedical progress arising from the greatly increased genetic information base generated by gene mapping and the sequencing of the complete Human Genome.

Considerable advances in the understanding and progress of treatment of schizophrenia are reflected in this totally revised and updated second edition. In many respects, the field of schizophrenia research has changed dramatically since the first edition of this book. There are now several genes that appear to be valid susceptibility factors for illness, and these discoveries will very probably lead to a new understanding of causation and to new targets for therapeutic intervention.