A cross-linguistic study of grammatical morphemes expressing spatial relationships that discusses the relationship between the way human beings experience space and the way it is encoded grammatically in language. The discussion of the similarities and differences among languages in the encoding and expression of spatial relations centers around the emergence and evolution of spatial grams, and the semantic and morphosyntactic characteristics of two types of spatial grams. The author bases her observations on the study of data from 26 genetically unrelated and randomly selected languages.