Leon S. Kennedy, Claire Redfield, Rebecca Chambers, and the survivors of the Caliban Cove incident are en route to Europe to rendezvous with the other surviving S.T.A.R.S. members for further operations against the evil Umbrella Corporation. John Andrews and David Trapp, two original characters created for the novels, help fill out the cast. While in the air, their plane is redirected by the mysterious Trent, an enigmatic figure who has been guiding and manipulating events throughout the entire series of novels. Trent informs the group of an Umbrella facility in Utah, used to test and train the company's experimental biological weapons. The facility's overseer, a man named Reston, is one of three people in the world in possession of a codebook which would allow access to all of Umbrella's most secret documents. Trent wants the group to infiltrate the facility, steal the codebook, and take down Umbrella once and for all....