The completion of a number of gene sequencing projects, recent advances in genomic and proteomic technologies, and the availability of powerful bioinformatics tools have led to promising new avenues and approaches in the search for cancer biomarkers. This book provides a comprehensive overview of current methodologies and technologies. It discusses biomarker discovery as a whole, rather than focusing on one specific marker or cancer. With information on both existing and potential biomarkers, Cancer Biomarkers: Analytical Techniques for Discovery:
* Provides insights into the current technological platforms for biomarker discovery, including mass spectrometry combined with multidimensional chromatography, DIGE, and various chip technologies
* Includes a detailed discussion of protein networks and protein phosphorylation in cancer
* Details the use of imaging mass spectrometry, laser capture microdissection, serial analysis of gene expression, enzyme-linked immunosorbent assays, protein microarrays, antibody-based microarrays, and bioinformatics
* Covers the emerging role of surface-enhanced laser desorption ionization (SELDI) and various tagging and labeling strategies
* Discusses related regulatory and ethical issues

Boasting almost one hundred pieces, The Oxford Book of Modern Science Writing is a breathtaking celebration of the finest writing by scientists--the best such collection in print--packed with scintillating essays on everything from "the discovery of Lucy" to "the terror and vastness of the universe."

Provides a reference for the names, and their meanings of all named minor planets. Informs about the discoverers as well as the circumstances of the discovery of all 10,666 minor planets numbered up to June 1999.

Maddy and her friend Cate are in Egypt on a school trip. They keep seeing a mysterious man in a black suit. Then they look in Cate's bag and are shocked at what they find. Should they tell somebody about their discovery? Why is the man in black following them?

Journeys of the Great Explorers
by Glyndwr Williams narrated by the author
Lecture 1 The World Before Columbus
Lecture 2 The Voyages of Christopher Columbus
Lecture 3 The Voyage of Vasco da Gama and the “Sea Road” to the East
Lecture 4 The First Circumnavigation: The Voyage of Ferdinand Magellan
Lecture 5 The Second Circumnavigation: The Voyage of Francis Drake
Lecture 6 The Tools of Discovery
Lecture 7 Life at Sea
Lecture 8 Voyages of Delusion: The Search for the Northwest Passage
Lecture 9 The Pacific Ocean: The Great Unknown
Lecture 10 The “Rambling Voyages” of William Dampier
Lecture 11 Vitus Bering and the Russian Discovery of America
Lecture 12 The Pacific Voyages of James Cook
Lecture 13 The Revolution in Navigation and Health
Lecture 14 The World After Cook
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