The book starts with an introduction to and history of myeloid-derived suppressor cells (MDSCs), followed by a description of their differentiation, their role in the tumour microenvironment and their therapeutic targeting. It closes with an outlook on future developments. In cancer patients, myelopoiesis is perturbed and instead of generating immunogenic myeloid cells (such as dendritic cells, inflammatory macrophages and granulocytes), there is an increase in highly immature MDSCs.
The topic of Antibiotic Use in Dermatology is reviewed in this issue of Dermatologic Clinics. Dr. James Del Rosso has assembled a panel of experts to pen articles on topics including Clinical Considerations in the Treatment of Acne Vulgaris and Other Inflammatory Skin Disorders, Topical Antibiotics in Dermatology, A Current Review of Topical Benzoyl Peroxide
There's more than heather shaking in Lochdubh when Constable Hamish Macbeth investigates the murder of a gorgeous television reporter whose inflammatory reportage and unscrupulous investigative tactics have incensed the entire village -- and left no shortage of suspects.
Pelvic Inflammatory Disease (Deadly Diseases and Epidemics)
Pelvic inflammatory disease (PID) is a sexually transmitted disease seen in women, and is usually caused by gonorrhea or chlamydia. PID most often occurs in adolescent and young women, and can be a silent infection that may go undetected for years. Undiagnosed and untreated, PID leads to many potentially severe and devastating health consequences in women of reproductive age, including infertility.
The broad field of neuro-ophthalmology encompasses lesions of both the afferent and efferent pathways, which can result from various etiologies: tumoral, paraneoplastic, vascular, inflammatory, infectious, or hereditary, just to name a few.