• COVER: Stem Cells: Poised for a Breakthrough - After eight years of political ostracism, stem-cell scientists like Harvard's Douglas Melton are coming back into the light--and making discoveries that may soon bring lifesaving breakthroughs • ESSAY: Obama's Fresh Start: Substance Over Showbiz - Obama has shifted the focus of the presidency from show biz to substance--at least for now • RELIGION: Rural Churches Grapple with a Pastor Exodus - The only group vanishing faster than the population in rural America is its pastors, stranding farm congregations and challenging church leaders to find new models • PEOPLE: 10 Questions for Mickey Rourke - After wrestling back into the spotlight, the actor looks ahead. Mickey Rourke will now take your questions