Working from basic chemical principles, Metals in Medicine presents a complete and methodical approach to the topic. Introductory chapters discuss important bonding concepts applicable to metallo-drugs and their biological targets, interactions that exist between the agents and substances in the biological milieu, basic pharmacokinetic and pharmacodynamic properties including transport and uptake of drugs by the cells, and methods for measuring efficacy and toxicity of agents. The steps from drug discovery to market place are also briefly outlined and discussed.
Clear instructions, clever projects, and colorful photography make this your go-to source for toys that are fun to make, lovely to give, and wonderful to receive.You'll find patterns for easy-to-crochet dolls and toy animals, complete with accessories and play clothes for them to wear, as well as a few unexpected surprises, like a plush mobile and soft alphabet blocks. Claire Garland shows you how to make basic shapes and forms and then encourages you to use your imagination to embellish them into fanciful playtime friends.
This text intends to provide the student with the knowledge of a geometry of greater scope than the classical geometry taught today, which is no longer an adequate basis for mathematics or physics, both of which are becoming increasingly geometric. The geometry of surfaces is an ideal starting point for students learning geometry...
In August and September 1999, a group of 68 physicists from 48 laboratories in 17 countries met in Erice, Italy, to participate in the 37th Course of the International School of Subnuclear Physics. This volume constitutes the proceedings of that meeting. It focuses on the basic unity of fundamental physics at both the theoretical and the experimental level.
Few faculty members in academic medical centres are formally prepared for their roles as teachers. This work is an introductory text designed to provide medical teachers with the core concepts of effective teaching practice and information about innovations for curriculum design, delivery, and assessment. It offers brief, focused chapters with content that is easily assimilated by the reader. Topics are relevant to basic science and clinical teachers, and the work does not presume readers possess prerequisite knowledge of education theory or instructional design.
