Two joggers are found murdered in San Francisco's Golden Gate Park, and the killings are bizarrely reminiscent of a Washington, D.C. case that Alex Cross has been unable to solve. He is called to San Francisco, and then learns of similar murders in eight cities from Las Vegas to Charleston. Together with a female San Francisco detective, Cross plunges into a menacing world where posing explodes into bloodlust and frenzy, even as he is being stalked by a terrifying criminal who calls himself the Mastermind.
Alex Cross calls them the Jane Doe murders. Each body has been dumped, abandoned without clothes, without ID. There is no set pattern to the killings and officially they are unconnected. But Alex knows that one man is responsible, a man who's living dangerously a new enemy he's named Weasel.
Killer Gary Soneji is back, filled with hatred and gaining revenge on detective Alex Cross. Nothing, not even death itself, is going to stand in his way.
Back on home territory after the "Kiss the Girls" case, Alex Cross faces his most harrowing challenge yet: a pair of ice-cold killers who are picking off the nation's rich and famous one by one with chilling professional efficiency.
As two serial killers terrorize different regions of America, the FBI begins to suspect that the two are competing with each other, and Washington, D.C. police detective Alex Cross embarks on a personal quest to find the perpetrators.