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Inhalation Toxicology



Inhalation Toxicology - 2d Ed.


PART I Inhalation Toxicology: Methods and Measurements
Chapter 1 Inhalation Risk Assessment at the Environmental Protection Agency 3
Chapter 2 The Development and Application of Acute Exposure Guideline Levels for Hazardous Substances 39
Chapter 3 Emergency Response Planning Guidelines (ERPGs) 61
Chapter 4 Directed-Flow Aerosol Inhalation Exposure Systems: Applications to Pathogens and Highly Toxic Agents 73
Chapter 5 Low-Level Effects of VX Vapor Exposure on Pupil Size and Cholinesterase Levels in Rats 91
Chapter 6 Application of Intratracheal Instillation Exposure to the Etiological Determination of a Pulmonary Disease
Outbreak: Nylon Flock as an Example 109
Chapter 7 The Use of Large Animals in Inhalation Toxicology 119
Chapter 8 Toxic Load Modeling 137
Chapter 9 Inhalation Toxicology and Carcinogenicity Studies of the National Toxicology Program 159
Chapter 10 Toxicology of Fire and Smoke 205

PART II Inhalation Toxicology Methods
Chapter 11 Toxicogenomics of Low-Level Nerve Agent Vapor Exposure 231
Chapter 12 Respiratory Sensitization 243
Chapter 13 Peripheral Chemosensory Irritation with Particular Reference to Respiratory Tract Exposure 269
Chapter 14 Role of Cytokines in Pulmonary Inflammation and Fibrosis Induced by Inhaled Mineral Particles 307
Chapter 15 Hormesis: Implications for Risk Assessment 335
Chapter 16 Nasal Toxicology 349
Chapter 17 Effects of Inhaled Toxicants on the Nose and Nasal Function 373
Chapter 18 Toxicokinetics: Deposition, Absorption, Distribution, and Excretion 405

Chapter 19 Mechanistic Determinants and Modeling of the Inhalation Pharmacokinetics of Volatile Organic Chemicals 439
Chapter 20 Inhalation Toxicology of an Irritant Gas—Historical Perspectives, Current Research, and Case Studies of Phosgene Exposure 457
Chapter 21 Inhalation Toxicology of Riot Control Agents 485
Chapter 22 Chemical Warfare Agents and Nuclear Weapons 521
Chapter 23 The Inhalation Toxicology of Chromium Compounds 543
Chapter 24 Safety Assessment of Therapeutic Agents Administered by the Respiratory Route 565
Chapter 25 Nonclinical Pharmacology and Safety Studies of Insulin Administered to the Respiratory Tract 609

PART III Inhalation Toxicology of Materials
Chapter 26 Inhalation Toxicology of Alcohol/Gasoline Fuels—Current Status 623
Chapter 27 Asbestos 647
Chapter 28 The Inhalation Toxicity of Benzene 669
Chapter 29 Carbon Monoxide 695
Chapter 30 Experimental, Clinical, Occupational Toxicology, and Forensic Aspects of Hydrogen Cyanide with Particular Reference to Vapor Exposure 717
Chapter 31 The Pharmacology and Toxicology of Inhaled Dusts, Endotoxins, and Glucans 803
Chapter 32 Fluorocarbon Alternatives—Methodologies for Special Studies and Results 825
Chapter 33 Animal Models for Three Major Cigarette-Smoke-Induced Diseases 851
Chapter 34 The Impact of Active and Passive Exposure to Cigarette Smoke on Maternal and Fetal Health 875

PART IV Inhalation Toxicology of Bioaerosols Chapter 35 Health Aspects of Bioaerosols 913
Chapter 36 Emerging Biothreats: Natural and Deliberate 933
Chapter 37 Toxicology Associated with Respiratory Exposures to Fungi (Molds) 945
Chapter 38 Inhalation Toxicity of Botulinum Neurotoxin 963
Chapter 39 Inhalation Ricin: Aerosol Procedures, Animal Toxicology, and Therapy 973
Chapter 40 Toxicity, Mechanisms, Prophylaxis, and Therapy of Inhaled Biological Toxins 983

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Tags: Toxicology, exposure, toxicology, testing, botulinum