This work lists the main diseases encountered by Médecins Sans Frontières (MSF) since 1971. It is intended for all medical professionals working in hospitals and clinics. The handbook has been thoroughly researched by taking into account MSF’ experience, recommendations made by reference organisations such as the WHO, and indications given by specialist workers. It has been designed as an effective and reliable source of information. Curative care is an integral part of medical programmes such as vaccination, mother-child care, water purification, environmental cleaning and nutrition. The manual can be used as a tool when developing a curative care policy.