This book tells of the escape of two dogs, Rowf and Snitter, from a government research station in the Lake District in England, where they had been horribly mistreated. They live on their own with help from a fox, or "tod," who speaks to them in a Geordie dialect. After the starving dogs attack some sheep on the fells, they are reported as ferocious man-eating monsters by a journalist. A great dog hunt follows, which is later intensified with the fear that the dogs could be carriers of a dangerous bioweapon, such as the bubonic plague.