The cardinal indicator of a satisfactory outcome for neonatal intensive care is normal neurological development, yet until very recently, clinical monitoring of brain function was limited to the physical examination. Recently, though, a number of new techniques have been developed to assist clinicians who wish to know more about the neurological status of their fragile patients.
Molecular Fluorescence: Principles and Applications
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Today, fluorescence
spectroscopy is an important tool of investigation in many areas. In
analytical sciences, its advantage is extremely high sensitivity and
selectivity - even single molecules can be detected - and it achieves a
high spatial resolution and time resolution in combination with
microscopic techniques or laser techniques, respectively. In material
sciences, this is used to study structure and dynamics of surfaces.
Particularly in the areas of biochemistry and molecular genetics,
fluorescence spectroscopy has become a dominating technique. Together
with the latest imaging techniques, fluorescence spectroscopy allows a
real-time observation of the dynamics of intact biological systems with
an unprecedented resolution.
This book offers a comprehensive introduction to and survey of
fluorescence spectroscopy. It is written for newcomers and active
researchers alike who are learning to apply fluorescence methods in the
areas of chemistry, physical chemistry, polymers, materials, colloids,
biochemistry, biology, medical and pharmaceutical research.
