Ivy League college notices of acceptance and rejection arrive at the luxurious Upper East Side homes of the Gossip Girls, and everyone's wondering about their futures. As college applications start to arrive, and the word gets around, gossip builds up as the stakes are raised and friendships are put to the test. For example, the friendship between the threesome that's been together forever, Blair, Serena, and Nate. Ever since the 4th grade Blair has had her heart set on Yale, and even named her new baby sister after the university. Despite these wishes, she completely blew both of her chances to get in, and is losing sleep at night from her nerves. Without her knowing, her on and off boyfriend Nate decided what the heck, and applied to Yale too. Also not even thinking about it was her best friend Serena when she decided to apply. College application day arrives, and Blair and Serena decide to open theirs together. Big mistake. Soon after their friendship will go downhill, but now, once again will they be able to pull it back up?
But hey, who cares about college when you have a love life to look after? Nate and Blair have been dating on and off since anyone can remember, and if you don't think they'll end up married, you're in the minority.